Flumatinib-d3 is deuterium labeled Flumatinib. Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRβ, and c-Kit with IC50s of 1.2 nM, 307.6 nM, and 665.5 nM, respectively.
- Deuterium labeled Flumatinib
- Orally available
- Selective inhibitor of Bcr-Abl
- Inhibits c-Abl with IC50 of 1.2 nM
- Inhibits PDGFRβ with IC50 of 307.6 nM
- Inhibits c-Kit with IC50 of 665.5 nM